Startup database
Pharma & Drug Discovery
Target discovery, molecule design and translational tooling, increasingly compute first.
52 companies
XtalPi
AI drug discovery
Combines quantum physics, artificial intelligence, and robotics for molecule discovery.
Insitro
AI drug discovery
Combines machine learning and high-throughput biology to transform drug discovery.
Recursion Pharmaceuticals
AI drug discovery
Combines automation and machine learning to industrialize drug discovery and development.
Relay Therapeutics
Structure based design
Applies structural biology and computational chemistry to target protein motion.
Exscientia
AI drug discovery
Uses AI to design patient first precision medicines and optimize clinical trials.
Valo Health
AI drug discovery
Integrates human data and machine learning to accelerate therapeutic discovery.
Schrodinger
Computational chemistry
Provides physics based software solutions to accelerate molecular discovery and design.
Insilico Medicine
AI drug discovery
Applies generative AI to discover new drug candidates and identify novel disease targets.
BenevolentAI
AI drug discovery
Employs an artificial intelligence platform to discover novel therapies for complex diseases.
Genesis Therapeutics
AI drug discovery
Uses deep learning and molecular simulations to discover small molecule drugs.
AbCellera
Antibody discovery
Discovers and develops antibody therapeutics using high throughput microfluidics.
Enveda Biosciences
Natural product discovery
Translates nature's chemistry into small-molecule therapeutics using AI and metabolomics.
Basecamp Research
AI-designed therapeutics
Frontier AI company designing medicines with EDEN, biological foundation models trained on a large proprietary evolutionary dataset.
Sling Therapeutics
Thyroid eye disease
Developing an oral small-molecule treatment for thyroid eye disease in a Phase 3 trial.
Terray Therapeutics
AI drug discovery
Combines ultra high throughput chemical synthesis with AI to find small molecules.
Atomwise
AI drug discovery
Utilizes deep learning for structure based small molecule drug discovery.
Plexium
Protein degradation
Discovers targeted monovalent protein degraders using high-throughput cellular screening.
Iambic Therapeutics
AI drug discovery
Accelerates drug discovery through generative AI and high-throughput physics models.
Evozyne
Protein design
Uses advanced machine learning to design highly functional synthetic proteins.
Verge Genomics
AI drug discovery
Discovers therapeutics for neurodegenerative diseases utilizing human genomic data.
Unlearn.AI
Clinical trial design
Creates digital twins of patients to run smaller and faster clinical trials.
Healx
Rare disease therapies
Uses artificial intelligence to discover and develop treatments for rare diseases.
Estuary Biotherapeutics
Kidney gene therapy
Developing kidney-directed gene therapies.
Causaly
Literature search and synthesis
Accelerates scientific research discovery through artificial intelligence driven literature synthesis.
Standigm
AI drug discovery
Employs deep learning workflows to streamline early-stage drug discovery projects.
RegCell
Cell therapy
Epigenetic reprogramming of auto-reactive T cells into antigen-specific regulatory T cells.
Profluent
Protein design
Generates custom proteins and gene-editing systems using deep learning models.
LabGenius
Protein design
Uses machine learning and robotic automation to discover novel protein therapeutics.
Peptone
Protein therapeutics
Designs therapeutic proteins using biophysics and advanced computational modeling.
Cradle
Protein design
Provides generative AI software for engineering proteins and optimizing cellular factories.
PostEra
AI drug discovery
Uses machine learning to automate medicinal chemistry and speed up drug synthesis.
Altis Labs
Clinical trial endpoints
AI imaging endpoints designed to predict survival outcomes earlier in oncology clinical trials.
VeriSIM Life
Translational prediction
Predicts clinical success of drug candidates using biosimulation and machine learning.
A-Alpha Bio
Protein design
Measures and models protein-protein interactions at scale using synthetic biology.
Pharos iBio
AI drug discovery
Uses deep learning to discover treatments for rare and orphan diseases.
HexemBio
Synthetic biology
Synthetic yolk sac platform that rejuvenates aged blood stem cells for transplant.
Iktos
AI drug discovery
Develops generative AI models for automated de novo drug design.
Graph AI
Pharmacovigilance AI
AI platform automating drug safety and pharmacovigilance workflows for life sciences companies.
Biorelate
Biomedical data curation
Extracts dark biomedical data from text to aid drug discovery.
InSilicoTrials
Clinical trial simulation
Provides computational modeling and simulation software for virtual drug trials.
Outer Bio
Human skin models and AI discovery
A discovery platform combining long-lived ex vivo human skin models with machine learning.
Prime Medicine
Prime editing
Prime editing company developing genetic therapies for inherited diseases.
Ultragenyx Pharmaceutical
Rare disease gene therapy
Rare-disease biotechnology company behind the first FDA-approved gene therapy for pediatric MPS IIIA.
Coefficient Bio
Generative biology
AI drug discovery company acquired by Anthropic and integrated into its life sciences team.
Anthropic
Frontier AI
Frontier AI company expanding Claude into scientific research and life sciences workflows.
Eli Lilly and Company
Targeted oncology
Global drugmaker behind Inluriyo, the oral SERD approved with Verzenio for ESR1 mutated breast cancer.
Egetis Therapeutics
Rare disease endocrinology
Rare disease drug developer behind Emcitate (tiratricol) for MCT8 deficiency.
Bayer
Cardiorenal medicines
Global life sciences company developing medicines across cardiology, nephrology, oncology and women's health.
IntraBio
Rare neurology
Rare disease company behind Aqneursa, approved for ataxia in ataxia telangiectasia.
Scholar Rock
Neuromuscular and rare diseases
A biopharmaceutical company developing medicines that target growth factors in their local tissue environments.
Panacea
AI-native FDA regulatory services
AI-native regulatory services for biotechnology and medical device companies.
Isomorphic Labs
AI drug discovery
Uses artificial intelligence and biological modeling to accelerate drug design.