
The $2.4B Oral Macrocycle and Bispecific Surge: Why Big Pharma Is Buying Platform Engines Over Single Assets
Dr. Dereck Mush, MD, MBADiscovers targeted monovalent protein degraders using high-throughput cellular screening.
Plexium develops targeted protein degradation therapeutics using a high-throughput cell-based screening platform. The technology allows pharmaceutical researchers to identify small molecules, such as monovalent degraders and molecular glues, that selectively target and destroy disease-causing proteins.
Notable investors: BVF Partners, TCG Crossover, Amgen Ventures, Vertex Ventures.

Dr. Dereck Mush, MD, MBAThe HealthTech Signal
Chai Discovery triples its valuation as pharma buys into AI-designed molecules
Dr. Dereck Mush, MD, MBA
Dr. Dereck Mush, MD, MBA
Dr. Dereck Mush, MD, MBA