How the Signal Score works
Total raised, quality of investors and recency of the last round.
Revenue trajectory, customer count, hiring and market pull.
Peer-reviewed evidence, FDA/CE clearances and live health-system deployments.
Founder track record, clinical depth on the bench and technical leadership.
Search presence, press coverage, founder and brand reach, and how often the company shows up where buyers look.
Scores are compiled by our research desk from public funding data, regulatory filings, published evidence and hiring signals, then refreshed monthly. Figures are estimates; if something looks wrong, .
September 2026: Inaugural Edition
This is the first monthly edition of the HealthTech Signal ranking. Placements reflect our scoring desk's assessment as of publication. As we expand our research and incorporate reader input, rankings may be updated ahead of the October edition. All material changes are logged on our methodology page.
- 1
TempusOperates a proprietary data and AI platform to power precision medicine and clinical decision support through genomic sequencing.AI & Clinical Intelligence • Chicago, USA • $1400M • Score 94.8AI & Clinical Intelligence$1400M94.8
- 2
Devoted HealthOperates as a Medicare Advantage plan provider integrated with its own virtual and home-based clinical group.Payers & Payments • Waltham, USA • $2100M • Score 94.4Payers & Payments$2100M94.4
- 3
RecursionCombines experimental biology and automation with machine learning to decode biology and industrialize drug discovery.Biotech & Discovery • Salt Lake City, USA • $1100M • Score 94.1Biotech & Discovery$1100M94.1
- 4
Hinge HealthDelivers digital physical therapy and clinical musculoskeletal care programs for chronic pain management to employers and health plans.Care Delivery • San Francisco, USA • $1000M • Score 94.1Care Delivery$1000M94.1
- 5
AledadePartners with independent primary care practices to build and manage physician-led Accountable Care Organizations.Care Delivery • Bethesda, USA • $410M • Score 93.7Care Delivery$410M93.7
- 6
WaystarProvides cloud-based software that simplifies healthcare billing, claims management, and payments for clinical organizations.Payers & Payments • Louisville, USA • $1040M • Score 93.6Payers & Payments$1040M93.6
- 7
Lyra HealthProvides comprehensive mental health benefits for employers, connecting employees to mental health coaching, therapy, and psychiatric care.Care Delivery • Burlingame, USA • $910M • Score 93.4Care Delivery$910M93.4
- 8
SchrodingerDevelops a physics-based computational platform that accelerates molecular discovery for therapeutics and materials science.Biotech & Discovery • New York, USA • $700M • Score 93.1Biotech & Discovery$700M93.1
- 9
Spring HealthDelivers personalized mental healthcare benefits to employers using a proprietary machine learning approach to match individuals with providers.Care Delivery • New York, USA • $370M • Score 92.7Care Delivery$370M92.7
- 10
ZelisProvides modern healthcare payments optimization, billing validation, and network analytics solutions for payers and providers.Payers & Payments • Bedminster, USA • $950M • Score 92.3Payers & Payments$950M92.3
- 11
NeuralinkDevelops ultra-high bandwidth brain-computer interfaces to connect human brains with computers.MedTech & Devices • Fremont, USA • $680M • Score 92.1MedTech & Devices$680M92.1
- 12
Komodo HealthProvides a healthcare map tracking longitudinal patient journeys to deliver real-world data and market intelligence.Data & Infrastructure • San Francisco, USA • $514M • Score 92Data & Infrastructure$514M92
- 13
Maven ClinicOperates a virtual clinic dedicated to family building, maternity, pediatric care, and menopause support for global employers.Care Delivery • New York, USA • $300M • Score 91.9Care Delivery$300M91.9
- 14
AbridgeGenerates real-time clinical documentation and structured data from patient-clinician conversations using proprietary generative AI.AI & Clinical Intelligence • Pittsburgh, USA • $212M • Score 91.8AI & Clinical Intelligence$212M91.8
- 15
WhoopManufactures a screen-free wearable device tracking physiological metrics like recovery, sleep, strain, and cardiovascular health.Consumer & Prevention • Boston, USA • $400M • Score 91.5Consumer & Prevention$400M91.5
- 16
TransMedicsProvides the Organ Care System, a portable warm-perfusion platform for preserving hearts, lungs, and livers.MedTech & Devices • Andover, USA • $350M • Score 91.4MedTech & Devices$350M91.4
- 17
TranscarentProvides an integrated health and care experience platform for employees of self-insured organizations.Care Delivery • Denver, USA • $450M • Score 91Care Delivery$450M91
- 18
Cityblock HealthDelivers tech-enabled primary care, behavioral health, and social services specifically for Medicaid and lower-income communities.Care Delivery • Brooklyn, USA • $890M • Score 90.9Care Delivery$890M90.9
- 19
Sword HealthProvides virtual physical therapy and musculoskeletal care using clinical-grade wearable sensors and interactive digital guidance.Care Delivery • New York, USA • $340M • Score 90.9Care Delivery$340M90.9
- 20
DatavantOffers a secure data-de-identification and linking platform to connect health data across providers, registries, and life sciences.Data & Infrastructure • San Francisco, USA • $830M • Score 90.7Data & Infrastructure$830M90.7
- 21
Insilico MedicineUtilizes generative AI to discover novel targets and design clinical-stage drug candidates across multiple therapeutic areas.Biotech & Discovery • Hong Kong • $400M • Score 90.7Biotech & Discovery$400M90.7
- 22
HeartFlowOffers non-invasive, AI-driven coronary artery analysis to help clinicians diagnose and manage patients with coronary artery disease.MedTech & Devices • Mountain View, USA • $750M • Score 90.6MedTech & Devices$750M90.6
- 23
Viz.aiUses artificial intelligence to analyze medical scans, accelerating diagnosis and treatment coordination for acute clinical conditions.AI & Clinical Intelligence • San Francisco, USA • $250M • Score 90.6AI & Clinical Intelligence$250M90.6
- 24
OuraProduces a smart ring tracking sleep, activity, temperature, and physiological trends to support wellness.Consumer & Prevention • Oulu, Finland • $150M • Score 90.3Consumer & Prevention$150M90.3
- 25
AidocDevelops clinical AI solutions that analyze medical imaging to flag urgent pathologies and coordinate patient care workflows.AI & Clinical Intelligence • Tel Aviv, Israel • $250M • Score 90.2AI & Clinical Intelligence$250M90.2
- 26
FlywireDelivers global payment software that automates billing and digital transaction processes for healthcare and education systems.Payers & Payments • Boston, USA • $400M • Score 90.1Payers & Payments$400M90.1
- 27
Oscar HealthOperates a consumer-centric, technology-driven health insurance platform offering individual, family, and small group plans.Payers & Payments • New York, USA • $1600M • Score 89.5Payers & Payments$1600M89.5
- 28
PathAIEmploys machine learning to improve the accuracy of pathology diagnosis and support the development of novel immunotherapies.AI & Clinical Intelligence • Boston, USA • $255M • Score 89.4AI & Clinical Intelligence$255M89.4
- 29
Included HealthOffers a comprehensive virtual care and navigation platform combining primary care, behavioral health, and healthcare advocacy services.Care Delivery • San Francisco, USA • $370M • Score 89.3Care Delivery$370M89.3
- 30
Omada HealthProvides virtual care programs focused on chronic condition management, including diabetes prevention, hypertension, and joint health.Care Delivery • San Francisco, USA • $450M • Score 89.1Care Delivery$450M89.1
- 31
AlmaProvides a practice-management platform enabling mental health clinicians to build independent practices and accept commercial insurance.Care Delivery • New York, USA • $220M • Score 89.1Care Delivery$220M89.1
- 32
Procept BioRoboticsDevelops the AquaBeam Robotic System for minimally invasive treatment of benign prostatic hyperplasia.MedTech & Devices • San Jose, USA • $280M • Score 88.8MedTech & Devices$280M88.8
- 33
CedarProvides a financial technology platform that modernizes the patient billing and payment experience for health systems.Payers & Payments • New York, USA • $350M • Score 88.7Payers & Payments$350M88.7
- 34
ExscientiaApplies an end-to-end AI platform to discover and design precision medicines for oncology and immunology.Biotech & Discovery • Oxford, UK • $500M • Score 88.4Biotech & Discovery$500M88.4
- 35
TruvetaAggregates de-identified clinical data from a cooperative network of member health systems to accelerate medical research.Data & Infrastructure • Bellevue, USA • $200M • Score 88.4Data & Infrastructure$200M88.4
- 36
OverjetBuilds AI-powered dental imaging analysis software to assist clinicians in diagnostic accuracy and clinical decision-making.AI & Clinical Intelligence • Boston, USA • $133M • Score 88.4AI & Clinical Intelligence$133M88.4
- 37
CMR SurgicalDevelops the Versius surgical robotic system, a modular and portable platform for minimally invasive surgery.MedTech & Devices • Cambridge, UK • $1100M • Score 88.3MedTech & Devices$1100M88.3
- 38
PaigeDesigns AI-powered digital pathology solutions to aid pathologists in detecting and diagnosing complex cancers.AI & Clinical Intelligence • New York, USA • $220M • Score 88.3AI & Clinical Intelligence$220M88.3
- 39
RoProvides a direct-to-consumer telehealth platform offering diagnostics, personalized treatment plans, and home delivery of medications.Care Delivery • New York, USA • $1000M • Score 88.2Care Delivery$1000M88.2
- 40
Clarify HealthDelivers an enterprise analytics platform that tracks clinical, financial, and operational performance for payers and systems.Payers & Payments • San Francisco, USA • $328M • Score 88.2Payers & Payments$328M88.2
- 41
LunitDevelops AI-powered diagnostic software for cancer screening, focusing on mammography and chest radiography analysis.AI & Clinical Intelligence • Seoul, South Korea • $135M • Score 88.1AI & Clinical Intelligence$135M88.1
- 42
TalkiatryProvides high-quality, in-network virtual psychiatric care, partnering with major health plans to make psychiatry accessible.Care Delivery • New York, USA • $140M • Score 88Care Delivery$140M88
- 43
Eko HealthCreates smart stethoscopes integrated with AI algorithms to detect heart murmurs and signs of cardiovascular disease.MedTech & Devices • Oakland, USA • $125M • Score 87.9MedTech & Devices$125M87.9
- 44
Qure.aiCreates AI algorithms for medical imaging analysis, specializing in chest X-ray and head CT interpretation in resource-limited settings.AI & Clinical Intelligence • Mumbai, India • $120M • Score 87.7AI & Clinical Intelligence$120M87.7
- 45
HeadspaceOffers a digital mental health platform featuring mindfulness resources, meditation guides, and on-demand clinical coaching and therapy.Care Delivery • Santa Monica, USA • $320M • Score 87.4Care Delivery$320M87.4
- 46
Grow TherapyConnects independent mental health therapists with clients while managing scheduling, clinical notes, and insurance billing.Care Delivery • New York, USA • $175M • Score 87.4Care Delivery$175M87.4
- 47
SukiProvides a voice-enabled clinical digital assistant that automates clinical documentation and administrative tasks for healthcare providers.AI & Clinical Intelligence • Redwood City, USA • $149M • Score 87.2AI & Clinical Intelligence$149M87.2
- 48
CleerlyUtilizes artificial intelligence to analyze coronary CT angiograms, providing detailed evaluations of cardiovascular disease and plaque.AI & Clinical Intelligence • Denver, USA • $248M • Score 87.1AI & Clinical Intelligence$248M87.1
- 49
NablaDevelops an ambient AI assistant that automatically generates clinical notes from medical consultations across multiple languages.AI & Clinical Intelligence • Paris, France • $43M • Score 87.1AI & Clinical Intelligence$43M87.1
- 50
AbsciApplies generative AI and high-throughput screening to design and validate novel therapeutic antibodies.Biotech & Discovery • Vancouver, USA • $230M • Score 87Biotech & Discovery$230M87
- 51
RedoxDelivers an API-driven healthcare integration platform that standardizes and transfers electronic health record data across systems.Data & Infrastructure • Madison, USA • $143M • Score 86.7Data & Infrastructure$143M86.7
- 52
CeribellCreates a rapid-response, wearable EEG headband and AI system for point-of-care seizure detection.MedTech & Devices • Sunnyvale, USA • $150M • Score 86.6MedTech & Devices$150M86.6
- 53
Ambience HealthcareProvides an AI operating system for healthcare organizations, offering automated documentation, coding, and clinical workflows.AI & Clinical Intelligence • San Francisco, USA • $120M • Score 86.5AI & Clinical Intelligence$120M86.5
- 54
Thyme CareProvides cancer care navigation and support, collaborating with oncologists and health plans to guide patients through oncology treatments.Care Delivery • Nashville, USA • $110M • Score 86.5Care Delivery$110M86.5
- 55
Kaia HealthDevelops digital therapeutic programs for chronic musculoskeletal pain and chronic obstructive pulmonary disease using advanced computer vision.Care Delivery • Munich, Germany • $125M • Score 86.2Care Delivery$125M86.2
- 56
Function HealthOffers a direct-to-consumer health platform providing comprehensive lab testing and longitudinal tracking of biomarker data.Consumer & Prevention • Austin, USA • $28M • Score 86.1Consumer & Prevention$28M86.1
- 57
Health GorillaOperates a national health information network and QHIN, facilitating secure clinical data exchange for digital health developers.Data & Infrastructure • Mountain View, USA • $100M • Score 85.8Data & Infrastructure$100M85.8
- 58
AliveCorDevelops medical-grade, smartphone-compatible electrocardiogram hardware and clinical AI detection software.MedTech & Devices • Mountain View, USA • $154M • Score 85.6MedTech & Devices$154M85.6
- 59
BiofourmisOffers a continuous remote monitoring and AI-driven clinical care platform for hospital-at-home models.MedTech & Devices • Boston, USA • $440M • Score 85.3MedTech & Devices$440M85.3
- 60
Genesis TherapeuticsLeverages deep learning and molecular simulations to discover small-molecule drugs for challenging targets.Biotech & Discovery • Burlingame, USA • $280M • Score 85.3Biotech & Discovery$280M85.3
- 61
Rad AIGenerates automated radiology report impressions to streamline radiologist workflows and reduce diagnostic turnaround times.AI & Clinical Intelligence • San Francisco, USA • $80M • Score 85.3AI & Clinical Intelligence$80M85.3
- 62
PrenuvoOffers AI-enhanced whole-body MRI screening scans designed to detect early-stage cancers, aneurysms, and silent health conditions.Consumer & Prevention • Redwood City, USA • $70M • Score 84.9Consumer & Prevention$70M84.9
- 63
Valo HealthEmploys an integrated cloud platform that utilizes human data to discover and develop therapeutic small molecules.Biotech & Discovery • Boston, USA • $450M • Score 84.8Biotech & Discovery$450M84.8
- 64
SynchronDevelops endovascular brain-computer interfaces implanted via the blood vessels to restore motor function.MedTech & Devices • Brooklyn, USA • $145M • Score 84.7MedTech & Devices$145M84.7
- 65
ArteraAIDevelops AI-enabled prognostic tests to personalize cancer therapy decisions and predict therapeutic benefits for patients.AI & Clinical Intelligence • San Francisco, USA • $115M • Score 84.7AI & Clinical Intelligence$115M84.7
- 66
Oshi HealthOperates a virtual gastrointestinal clinic providing multidisciplinary care for patients with chronic digestive conditions.Care Delivery • New York, USA • $60M • Score 84.7Care Delivery$60M84.7
- 67
Hippocratic AIBuilds safety-focused, voice-based generative AI foundation models tailored specifically for healthcare applications and clinical workflows.AI & Clinical Intelligence • Palo Alto, USA • $120M • Score 84.6AI & Clinical Intelligence$120M84.6
- 68
Carbon HealthOperates a modern healthcare network offering hybrid primary care, urgent care, and virtual clinical services.Care Delivery • San Francisco, USA • $520M • Score 84.5Care Delivery$520M84.5
- 69
CaresyntaxProvides an enterprise-level surgical intelligence platform that aggregates data from operating room devices to improve outcomes.MedTech & Devices • Boston, USA • $200M • Score 84.5MedTech & Devices$200M84.5
- 70
PelagoOffers a digital clinic for substance use management, providing virtual coaching, medical therapy, and cognitive behavioral therapy.Care Delivery • New York, USA • $151M • Score 84.4Care Delivery$151M84.4
- 71
Folx HealthDelivers virtual healthcare services tailored specifically to the needs of the LGBTQIA+ community, including hormone therapy.Care Delivery • Boston, USA • $85M • Score 84.2Care Delivery$85M84.2
- 72
AkasaApplies AI and machine learning to automate complex hospital revenue cycle management tasks and workflows.Payers & Payments • South San Francisco, USA • $85M • Score 83.8Payers & Payments$85M83.8
- 73
NursaProvides a digital healthcare staffing platform that matches hospitals and post-acute facilities with independent clinicians for open shifts.Care Delivery • Salt Lake City, USA • $100M • Score 83.4Care Delivery$100M83.4
- 74
Ribbon HealthProvides an API data platform supplying accurate information on healthcare providers, insurance networks, and care quality.Data & Infrastructure • New York, USA • $75M • Score 83.2Data & Infrastructure$75M83.2
- 75
Noah MedicalCreates robotic platforms for early lung cancer diagnosis, featuring the Galaxy bronchoscope system.MedTech & Devices • San Carlos, USA • $150M • Score 83.1MedTech & Devices$150M83.1
- 76
CortiDevelops a voice-based AI diagnostic co-pilot that assists clinicians during patient consultations and emergency triage situations.AI & Clinical Intelligence • Copenhagen, Denmark • $45M • Score 82.9AI & Clinical Intelligence$45M82.9
- 77
PulmonxManufactures minimally invasive medical devices for treating severe emphysema, including the Zephyr Endobronchial Valve.MedTech & Devices • Redwood City, USA • $200M • Score 82.8MedTech & Devices$200M82.8
- 78
Medical MicroinstrumentsBuilds the Symani Surgical System, a robotic platform designed specifically for open microsurgery and lymphatic reconstruction.MedTech & Devices • Pisa, Italy • $200M • Score 82.7MedTech & Devices$200M82.7
- 79
Butterfly NetworkCreates a handheld, single-probe whole-body ultrasound system powered by Ultrasound-on-Chip technology.MedTech & Devices • Burlington, USA • $400M • Score 82.4MedTech & Devices$400M82.4
- 80
SmarterDxUses clinical AI to audit medical charts, ensuring complete documentation, accurate coding, and revenue integrity for health systems.AI & Clinical Intelligence • New York, USA • $50M • Score 82.3AI & Clinical Intelligence$50M82.3
- 81
Terray TherapeuticsUses ultra-high-throughput chemistry and generative AI to design small-molecule therapeutics.Biotech & Discovery • Pasadena, USA • $140M • Score 82.1Biotech & Discovery$140M82.1
- 82
OrganoxCreates normothermic machine perfusion devices designed to preserve donor livers at physiological temperature before transplantation.MedTech & Devices • Oxford, UK • $50M • Score 82.1MedTech & Devices$50M82.1
- 83
Atropos HealthGenerates real-world evidence on-demand using AI to help clinicians make personalized, data-driven decisions for patients.AI & Clinical Intelligence • Palo Alto, USA • $47M • Score 82.1AI & Clinical Intelligence$47M82.1
- 84
Outset MedicalProduces the Tablo Hemodialysis System, an all-in-one consumer-friendly dialysis platform for clinical and home use.MedTech & Devices • San Jose, USA • $380M • Score 82MedTech & Devices$380M82
- 85
RegardOffers a clinical decision support platform that reviews patient charts to recommend diagnoses and prevent medical errors.AI & Clinical Intelligence • Los Angeles, USA • $50M • Score 81.9AI & Clinical Intelligence$50M81.9
- 86
LevelsProvides software that pairs with continuous glucose monitors to help consumers track metabolic health and nutrition.Consumer & Prevention • New York, USA • $50M • Score 81.3Consumer & Prevention$50M81.3
- 87
DistalmotionManufactures the Dexter robotic surgery system, combining laparoscopy with robotic precision in a hybrid approach.MedTech & Devices • Lausanne, Switzerland • $240M • Score 81.2MedTech & Devices$240M81.2
- 88
Cala HealthDevelops wearable neuromodulation therapies, specifically wrist-worn devices that deliver customized stimulation to treat essential tremors.MedTech & Devices • San Mateo, USA • $150M • Score 80.9MedTech & Devices$150M80.9
- 89
EzraUses AI to optimize full-body MRI cancer screenings, making scans faster, more accurate, and more affordable.Consumer & Prevention • New York, USA • $41M • Score 80.9Consumer & Prevention$41M80.9
- 90
Particle HealthProvides a user-friendly API that aggregates and correlates electronic health record data from national networks.Data & Infrastructure • New York, USA • $39M • Score 80.5Data & Infrastructure$39M80.5
- 91
PlumeOffers virtual gender-affirming hormone therapy, coaching, and support services to the transgender and nonbinary community.Care Delivery • Denver, USA • $38M • Score 80.5Care Delivery$38M80.5
- 92
OpenEvidenceDelivers AI-powered clinical decision support, providing evidence-based answers to medical questions sourced directly from peer-reviewed literature.AI & Clinical Intelligence • San Francisco, USA • $25M • Score 80.5AI & Clinical Intelligence$25M80.5
- 93
NoyoOffers API-driven infrastructure that connects health insurance carriers with benefits software platforms for modern enrollment solutions.Data & Infrastructure • San Francisco, USA • $45M • Score 80.1Data & Infrastructure$45M80.1
- 94
InsideTrackerAnalyzes blood, DNA, and fitness tracker data to deliver personalized, evidence-based nutrition and lifestyle recommendations.Consumer & Prevention • Cambridge, USA • $28M • Score 80.1Consumer & Prevention$28M80.1
- 95
Candid HealthDevelops an automated medical billing platform and API that allows digital health companies to manage claims and revenue.Payers & Payments • San Francisco, USA • $45M • Score 79.6Payers & Payments$45M79.6
- 96
SignosPairs continuous glucose monitoring hardware with AI-driven software to guide personalized nutrition and weight loss.Consumer & Prevention • San Mateo, USA • $37M • Score 79.3Consumer & Prevention$37M79.3
- 97
EchoNousDevelops point-of-care ultrasound devices integrated with deep-learning AI for cardiac and abdominal imaging.MedTech & Devices • Redmond, USA • $150M • Score 78.9MedTech & Devices$150M78.9
- 98
DeepScribeCreates an ambient AI clinical documentation platform that extracts structured medical data directly from natural patient conversations.AI & Clinical Intelligence • San Francisco, USA • $37M • Score 78.9AI & Clinical Intelligence$37M78.9
- 99
Virtual IncisionDevelops MIRA, a miniaturized, portable robotic-assisted surgery platform for abdominal procedures.MedTech & Devices • Lincoln, USA • $100M • Score 78.8MedTech & Devices$100M78.8
- 100
EnliticStandardizes and cleanses medical imaging data using clinical AI to improve workflow efficiency and data interoperability.AI & Clinical Intelligence • Fort Collins, USA • $70M • Score 78.7AI & Clinical Intelligence$70M78.7
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