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Rank 91Care Delivery

Plume

Offers virtual gender-affirming hormone therapy, coaching, and support services to the transgender and nonbinary community.

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Signal Score
80.5
Total raised
$38M
Stage
Series B
Founded
2019
Headquarters
Denver, USA
Region
North America

Their signal

Plume has built a highly trusted specialty clinic, pioneering safe, scalable, and fully virtual gender-affirming care that drastically lowers barriers to life-saving healthcare.

Signal Score 80.5editorial estimate, see how it is built
Capital (25% weight)76

Total raised, quality of investors and recency of the last round.

Growth (25% weight)81

Revenue trajectory, customer count, hiring and market pull.

Clinical & regulatory (20% weight)80

Peer-reviewed evidence, FDA/CE clearances and live health-system deployments.

Team (15% weight)85

Founder track record, clinical depth on the bench and technical leadership.

Online visibility (15% weight)83

Search presence, press coverage, founder and brand reach, and how often the company shows up where buyers look.

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